AJTMH HINARI
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med., s1-26(3), 1946, pp. 345-350
Copyright © 1946 by American Journal of Tropical Medicine

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kessel, J. F.
Right arrow Articles by Schireson, R.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Kessel, J. F.
Right arrow Articles by Schireson, R.

Emergency Sterilization of Drinking Water with Heteropolar Cationic Antiseptics

I. Effectiveness against Cysts of Endamoeba histolytica1,2,

John F. Kessel, Frederick J. Moore, F. M. Kaplan AND R. Schireson
From the Departments of Bacteriology and Experimental Medicine, University of Southern California School of Medicine, and from the Laboratories of the Los Angeles County Hospital

Although there are many practical uses for antiseptics which are effective against cysts of Endamoeba histolytica, one of the most important and difficult is the emergency sterilization of drinking water under military combat conditions. Various halogen preparations have not been entirely satisfactory because they tend to be inactivated by organic nitrogenous material and by alkalinity. Since natural waters encountered in the field may sometimes contain very high concentrations of organic nitrogenous material or may be alkaline, and since military emergency conditions in the field require uniform dosage, it is necessary to use the halogens in high initial concentrations under all conditions so that they may prove effective even under the worst conditions. These high concentrations of the halogens are distasteful and may not be entirely without toxicity.

The antiseptic activity of certain heteropolar cationic compounds, or synthetic, cationic detergents, was described in 1935 by Domagk (1) and Katz and Lipsitz (2).


1 The work reported in this paper was conducted under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and the University of Southern California.


2 Read at the Annual Meeting of the American Society of Tropical Medicine at Cincinnati, Ohio, November 14, 1945.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1946 by the American Society of Tropical Medicine and Hygiene.