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The Treatment of Oxyuriasis¹

1. Treatment of oxyuriasis was undertaken in three institutionalized groups.

2. In the home J. C. 38 per cent of the individuals (23 girls and 35 boys) were found infected with Enterobius vermicularis. Rigid hygienic measures were carried out over a period of six weeks, but a 13 per cent increase in incidence occurred.

3. In the home H. H. 97 per cent of 122 boys, and in the home P. E. 81 per cent of 26 girls were found infected. Treatment of the infected boys and girls with Seal-Ins coated gentian violet medicinal in varying dosages resulted in a cure of approximately 90 per cent.

4. The untoward symptoms of gentian violet medication were not serious. Vomiting, although prevalent, was noted infrequently per individual dose; however, it was found to occur more frequently in females than in males.

5. The difference between the cure of the individual with gentian violet and the eradication of the infection in an institution is emphasized.

Received November 22, 1939.
¹ Tulane Amebiasis Unit, National Institute of Health in collaboration with the Parasitology Laboratory, Department of Tropical Medicine, Tulane University, New Orleans, La., under the direction of Ernest Carroll Faust.

This study was made possible through the kind permission of Doctors Maud Loeber, Herbert Weinberger, Isidore Cohn, and Julian Graubarth, physicians in charge for the medical care of the children examined. We wish to express our indebtedness to them as well as to the Fathers, superintendents and nurses in the institutions surveyed, for their sincere and helpful coöperation during this study.

Read at the thirty-fifth annual meeting of the American Society of Tropical Medicine at Memphis, Tennessee, November 21–24, 1939.