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On Strains or Races of the Malaria Parasites¹

The observations discussed indicate that well-fixed subspecific varieties, strains, or races of two species at least of the human plasmodia are discernible immunologically. These differences in some cases are correlated with clear-cut variations in the characteristics of the clinical infection. Meager observations suggest that some strains may have a localized habitat or geographical distribution. In some instances this localization may represent an extreme degree of adaptation to species or races of the definitive hosts of the same faunal region.

Received September 20, 1939.
¹ The studies and observations on which this paper is based were conducted with the support and under the auspices of the International Health Division of The Rockefeller Foundation, in cooperation with the Florida State Board of Health and the Florida State Hospital.