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Am. J. Trop. Med., s1-18(5), 1938, pp. 609-617
Copyright © 1938 by American Journal of Tropical Medicine

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Studies on Oxyuriasis

VII. CLINICAL IMPROVEMENT FOLLOWING TREATMENT WITH SINGLE DOSES OF TETRACHLORETHYLENE

Willard H. Wright, John Bozicevich AND Leon S. Gordon
From the Division of Zoology, National Institute of Health, U. S. Public Health Service, and the Medical Department of the Metropolitan Police Boys' Club, Washington, D. C.

Among 50 boys of school age treated for oxyuriasis with single doses of tetrachlorethylene, clinical improvement occurred in a number of cases as indicated by gains in weight, amelioration of certain symptoms, and changes for the better in social attitude and scholastic standing.

Thirty-seven of 44 boys gained an average of 2.74 pounds each in weight in the 2 weeks following treatment; 4 boys lost an average of 3 pounds each during this period; and 3 showed no change in weight.

Information supplied by parents indicated improvement following treatment in a varying percentage of the boys who exhibited, before treatment, certain symptoms usually associated with pinworm infestation.

Questionnaires answered by the school teachers of 24 of the boys indicated that 10 of them exhibited definite improvement in their social attitude and scholastic standing within the 2 months immediately following treatment; in the cases of 9 of the boys no change was noted; in the opinion of the teacher the behavior of 2 of the boys was definitely worse; while replies covering 3 cases were of a mixed character indicating changes in attitude for both better and worse.

The need for detailed studies concerning the clinical features of oxyuriasis is pointed out, since in this regard there appears to be a dearth of reliable data based on adequate surveys of a sufficient number of cases.

Received July 16, 1937.





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Copyright © 1938 by the American Society of Tropical Medicine and Hygiene.