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The Effects of a High Vegetable Protein Diet on the Trichomonad Flagellates of Rats¹

Three groups of 10 rats each highly infected with intestinal trichomonads were fed on (1) a normal diet, (2) a high animal protein diet and (3) a high vegetable protein diet respectively for from ten to fourteen days. The rats were then killed, the cecal contents diluted with normal saline solution, and the number of trichomonads present counted with a haemocytometer.

The results obtained show a decided effect of the high protein diets on the number of trichomonads present. The average number per cubic millimeter in the rats fed on a normal diet was 8,270, in those fed on a high animal protein diet, 200, and in those fed on a high vegetable protein diet, 1,137. These data indicate that vegetable protein is nearly as effective as animal protein in rendering the intestinal environment of the rat host unfavorable for trichomonad flagellates.

¹ This work was aided by a grant from the Committee on Scientific Research of the American Medical Association. The writer is indebted to Miss Lydia Eskridge for technical assistance.