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"Brucellin," a Possible Specific for Undulant Fever in Man

Preliminary Report¹

The treatment of undulant fever has occupied the minds of investigators in this subject and practicing physicians since the time of the first discovery of one of the causative species of the genus by Bruce. Although many agents have been reported on and proposed for the specific treatment of the disease, it has been difficult to evaluate their efficacy due to the nature of the disease and to the fact that their use has been limited to a small number of cases. No attempt will be made here to review the agents that have been used with reported success or to discuss their value since this paper is only preliminary to a more extensive report which will appear later.

This laboratory has been engaged in the study of the therapeutic value of various agents in the treatment of Brucella infection in animals and man for a number of years.

¹ Journal Article Number 146 (n.s.) from the Michigan State Experiment Station. This study was partly financed by a grant from the Abortion Committee of the National Research Council and the Commonwealth Fund.