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Anthelmintics and their Uses in Medical and Veterinary Practice

By R. N. CHOPRA, M.A., M.D., (Cantab.), Major, Indian Medical Service, and ASA C. CHANDER, M.Sc., Ph.D., Professor of Biology, Rice Institute, Houston, Texas. Pp. xii, 1–253 with, in addition, a bibliography of 21 pages and an Index. The Williams & Wilkins Company, Baltimore, 1928

The text presents a logical arrangement. Section I contains a general treatment of the anthelmintics, an excellent summary of the helminths of man and domestic animals, and a discussion of the correlation between chemical composition of the drugs and their anthelmintic action. The subtitle of Section II is "Anthelmintics Acting on Parasites in the Gut." The particular drugs used in the treatment of the cestodes and the nematodes are here considered: Male Fern, Pelletierine, Carbon Tetrachloride, Chenopodium, Santonin, Thymol, Beta Naphthol, and numerous others, some of them even of slight or doubtful value. Certain proprietary preparations are also discussed. Section III deals with "Anthelmintics used against somatic parasitic infections," the various antimony preparations and emetine.

The more important drugs receive extensive treatment. For example, Carbon Tetrachloride is presented in outline as follows: Historical and General, Chemistry, Impurities and Tests for them, Pharmacological Action, Toxicology, Dosage and Methods of Administration, Effectiveness, Uses in Animals, and the Combination of Carbon Tetrachloride and Chenopodium.