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Am. J. Trop. Med., s1-10(1), 1930, pp. 57-64
Copyright © 1930 by American Journal of Tropical Medicine

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Nodular Fibrosis of the Spleen Associated with Filaria Loa1

Oskar Klotz
From the Department of Pathology, University of Toronto, Toronto, Canada

1. Groups of microfilariae aggregate in the spleen of some cases of Filaria loa infection.
2. These areas of localization are associated with an inflammatory reaction and fibrosis.
3. A tissue eosinophilia accompanies the filarial inflammation.
4. These reactions in the spleen may be analogous to the external chronic Calabar swellings.


1 The observations on which this paper is based were conducted under the auspices of the International Health Division.






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Copyright © 1930 by the American Society of Tropical Medicine and Hygiene.