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Trial of an Indirect Hemagglutination Test for the Diagnosis of Infections with Clonorchis Sinensis^*

Guillermo Pacheco, Dale E. Wykoff AND Rodney C. Jung

An indirect tanned-cell hemagglutination test was used for the detection of Clonorchis sinensis infections in man and rabbits. A comparison of the results from this test with those obtained earlier from a complement fixation test in which the same extract and the same sera were used showed the tanned-cell hemagglutination test to be relatively more sensitive. Specificity as well as sensitivity of the test was found to be increased by treating the dried worms with ether prior to saline extraction. With the ether treated material cross reactions were lacking in tests of a limited number of sera from animals and humans with Schistosoma and Paragonimus infections.

^* Supported by Grant E-1159 of the National Institute of Allergy and Infectious Diseases, U.S. Public Health Service.

Present address: USAREUR Medical Laboratory, APO 180, New York, New York.