HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Schwink, T. M. Search for Related Content PubMed PubMed Citation Articles by Schwink, T. M.

The Effect of Anti-Erythrocytic Antibodies upon Plasmodium Berghei Infections in White Mice^*

Thomas M. Schwink

Serum from rabbits immunized against normal mouse erythrocytes was administered to mice infected with Plasmodium berghei in six experiments involving a total of 105 mice. These mice were given three to eight daily serum injections, starting shortly before infection or 2 days after infection. Mice receiving this serum experienced severe infections and death earlier than did infected control mice. The blood of immune serum recipients contained high percentages of immature erythrocytes, most of which were parasitized. Normal rabbit serum had no effect upon the course of the infection in the one experiment in which such serum was used.

In two of the six experiments, immune serum recipients showed lower parasitemias than did control mice early in the course of the infection. This response was very transient and these mice later showed higher parasite counts than did the control mice.

^* This study was supported by a grant from the Rutgers University Research Council.

Present address: Division of Veterinary Science, College of Agriculture, University of Wyoming, Laramie, Wyoming.