AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 81(4), 2009, pp. 611-614
doi:10.4269/ajtmh.2009.09-0126;
Copyright © 2009 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Google Scholar
Right arrow Articles by Bukirwa, H.
Right arrow Articles by Dorsey, G.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bukirwa, H.
Right arrow Articles by Dorsey, G.

SHORT REPORT


Assessing the Impact of Indoor Residual Spraying on Malaria Morbidity Using a Sentinel Site Surveillance System in Western Uganda

Hasifa Bukirwa*, Vincent Yau, Ruth Kigozi, Scott Filler, Linda Quick, Myers Lugemwa, Gunawardena Dissanayake, Moses Kamya, Fred Wabwire-Mangen, AND Grant Dorsey
Uganda Malaria Surveillance Project, Kampala, Uganda; School of Public Health, University of California, Berkeley, California; Centers for Disease Control and Prevention, Atlanta, Georgia; National Malaria Control Programme, Uganda Ministry of Health, Kampala, Uganda; US Agency for International Development, Kampala, Uganda; Makerere University Medical School, Kampala, Uganda; Makerere University School of Public Health, Kampala, Uganda; Department of Medicine, University of California, San Francisco, California

 

ABSTRACT

A single round of indoor residual spraying (IRS) using lambda-cyhalothrin was implemented in a district of Uganda with moderate transmission intensity in 2007. Individual patient data were collected from one health facility within the district 8 months before and 16 months after IRS. There was a consistent decrease in the proportion of patients diagnosed with clinical malaria after IRS for patients < 5 and > 5 years of age (52% versus 26%, P < 0.001 and 36% versus 23%, P < 0.001, respectively). There was a large decrease in the proportion of positive blood smears in the first 4 months after IRS for patients < 5 (47% versus 14%, P < 0.001) and > 5 (26% versus 9%, P < 0.001) years of age, but this effect waned over the subsequent 12 months. IRS was effective in reducing malaria morbidity, but this was not sustained beyond 1 year for the proportion of blood smears read as positive.

Received March 12, 2009. Accepted for publication June 4, 2009.

Acknowledgments: We thank Tim Bruckner (School of Public Health, UC Berkeley) for help with the analysis process. We also thank the staff of Kihihi Health Centre who collected the patient data. Special thanks to all members of UMSP and particularly the data management team of Stella Kakeeto, Patience Aweko, and Rita Kabuleta, and the drivers Charles Mukasa and Henry Wambuzi for their dedication and effort.

Financial support: This study received financial support from the President’s Malaria Initiative through a cooperative agreement with the Centers for Disease Control and Prevention (U50/CCU925122).

* Address correspondence to Hasifa Bukirwa, Uganda Malaria Surveillance Program, c/o Infectious Diseases Research Collaboration, PO Box 7475, Kampala, Uganda. E-mail: hbukirwa{at}muucsf.org

Authors’ addresses: Hasifa Bukirwa, Uganda Malaria Surveillance Program, c/o Infectious Diseases Research Collaboration, PO Box 7475, Kampala, Uganda, Tel: 256-7126-68632/4154-0624, Fax: 256-4154-0524, E-mail: hbukirwa{at}muucsf.org. Vincent Yau, Department of Epidemiology c/o University of California, Berkeley, Haviland Hall, UC Berkeley, Berkeley, CA 94703, Tel: 408-507-9965, E-mail: vincentmyau{at}gmail.com. Ruth Kigozi, Uganda Malaria Surveillance Program, c/o Infectious Diseases Research Collaboration, PO Box 7475, Kampala, Uganda, Tel: 256-7723-97777/4154-0624, Fax: 256-4154-0524, E-mail: rkigozi{at}muucsf.org. Scott Filler, Malaria Branch, Division of Parasitic Disease, c/o Centers for Disease Control and Prevention, 4770 Buford Highway NE, Mail-stop F-22, Atlanta, GA 30341, Tel: 770-488-7793, Fax: 770-488-4206, E-mail: SFiller{at}cdc.gov. Linda Quick, Malaria Branch, Division of Parasitic Disease, c/o Centers for Disease Control and Prevention, 4770 Buford Highway NE, Mail-stop F-22, Atlanta, GA 30341, Tel: 770-488-7595, Fax: 770-488-4206, E-mail: maq2{at}CDC.GOV. Myers Lugemwa, National Malaria Control Programme, c/o Ministry of Health, Plot 6 Lourdel Road, Wandegeya, PO Box 7272, Kampala, Uganda, Tel: 256-7724-66941, Fax: 256-41-340887, E-mail: myers_1956{at}hotmail.com. Gunawardena Dissanayake, c/o US Agency for International Development, US Mission Compound South Wing, Plot 1577, Ggaba Road, PO Box 7856, Kampala, Uganda, Tel: 256-41-306-001, Ext. 6579, Fax: 256-41-306-661, E-mail: gdissanayake{at}usaid.gov. Moses Kamya, Department of Medicine, Makerere University Medical School, PO Box 7072, Kampala, Uganda, Tel: 256-414-533200/712-520469, Fax: 256-414-540-524, E-mail: mkamya{at}infocom.co.ug. Fred Wabwire-Mangen, Makerere Univesrity School of Publc Health, PO Box 7072, Kampala, Uganda, Tel: 256-7727-32206/4145-43872, Fax: 256-415-40524, E-mail: fwabwire{at}musph.ac.ug. Grant Dorsey, University of California, San Francisco, Box 0811, San Francisco, CA 94143, Tel: 415-206-4680, Fax: 415-648-8425, E-mail: gdorsey{at}medsfgh.ucsf.edu.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2009 by the American Society of Tropical Medicine and Hygiene.