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Am. J. Trop. Med. Hyg., 80(5), 2009, pp. 819-823
Copyright © 2009 by The American Society of Tropical Medicine and Hygiene

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Laboratory Assessment of a Gravity-Fed Ultrafiltration Water Treatment Device Designed for Household Use in Low-Income Settings

Thomas Clasen*, Jaime Naranjo, Daniel Frauchiger, AND Charles Gerba
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, England; Department of Soil, Water and Environmental Science, University of Arizona, Tucson, Arizona; and Vestergaard Frandsen S.A., Lausanne, Switzerland

Interventions to improve water quality, particularly when deployed at the household level, are an effective means of preventing endemic diarrheal disease, a leading cause of mortality and morbidity in the developing world. We assessed the microbiologic performance of a novel water treatment device designed for household use in low-income settings. The device employs a backwashable hollow fiber ultrafiltration cartridge and is designed to mechanically remove enteric pathogenic bacteria, viruses, and protozoan cysts from drinking water without water pressure or electric power. In laboratory testing through 20,000 L (~110% of design life) at moderate turbidity (15 nephelometric turbidity unit [NTU]), the device achieved log10 reduction values of 6.9 for Escherichia coli, 4.7 for MS2 coliphage (proxy for enteric pathogenic viruses), and 3.6 for Cryptosporidium oocysts, thus exceeding levels established for microbiological water purifiers. With periodic cleaning and backwashing, the device produced treated water at an average rate of 143 mL/min (8.6 L/hour) (range 293 to 80 mL/min) over the course of the evaluation. If these results are validated in field trials, the deployment of the unit on a wide scale among vulnerable populations may make an important contribution to public health efforts to control intractable waterborne diseases.


Received September 22, 2008. Accepted for publication December 14, 2008.

Disclosure: The authors note the following potential conflicts of interest: Thomas Clasen is a member of the Environmental Health Group of the London School of Hygiene and Tropical Medicine, a portion of whose funding is provided by Vestergaard Frandsen S.A., the manufacturer of the LifeStraw Family Filter; Daniel Frauchinger is an employee of Vestergaard Frandsen S.A.; and the costs of the University of Arizona in performing the laboratory work reported in this work were funded by Vestergaard Frandsen S.A.

* Address correspondence to Thomas Clasen, Disease Control and Vector Biology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St., London WC1E 7HT, UK. E-mail: thomas.clasen{at}lshtm.ac.uk

Authors’ addresses: Thomas Clasen, Disease Control and Vector Biology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St., London WC1E 7HT, UK, E-mail: thomas.clasen{at}lshtm.ac.uk. Jamie Naranjo and Charles Gerba, Department of Soil, Water and Environmental Sciences, University of Arizona, Tucson, AZ 85721. Daniel Frauchiger, Vestergaard Frandsen S.A., Chemin de Messidor 5-7, CH-1006, Lausanne, Switzerland.







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