AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 80(2), 2009, pp. 172-175
Copyright © 2009 by The American Society of Tropical Medicine and Hygiene

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Right arrow Leishmaniasis

Efficacy of Cryotherapy versus Intralesional Meglumine Antimoniate (Glucantime) for Treatment of Cutaneous Leishmaniasis in Children

Pouran Layegh*, Fakhrozaman Pezeshkpoor, Amir Hossein Soruri, Parisa Naviafar, AND Toktam Moghiman
Qaem Hospital, Mashad University of Medical Sciences, Mashad, Iran

We compared intralesional glucantine and cryotherapy for treatment of children with cutaneous leishmaniasis in Iran. We observed that cryotherapy is an effective treatment for cutaneous leishmaniasis in children. No serious posttreament side effects were observed in either group. At six months of follow-up, no recurrence of disease was observed in cured patients in either group. Because of its simplicity, lower cost, low rate of serious complications, and greater tolerability, cryotherapy should be recommended as an appropriate alternative treatment for leishmaniasis in children.

Received February 2, 2008. Accepted for publication October 27, 2008.

Acknowledgment: We thank Dr. Mohammad Taghi Shakeri for guidance and valuable comments regarding statistical analysis.

* Address correspondence to Pouran Layegh, Qaem Hospital, Mashad University of Medical Sciences, Mashad, Iran. E-mail: pouran_layegh{at}yahoo.com

Authors’ addresses: Pouran Layegh and Fakhrozaman Pezeshkpoor, Qaem Hospital, Mashad University of Medical Sciences, Mashad, Iran, E-mails: Pouran_layegh{at}yahoo.com, Layeghpo{at}mums.ac.ir, and Pezeshkpoorf{at}mums.ac.ir. Amir Hossein Soruri, Parisa Naviafar, and Toktam Moghiman, Mashad University of Medical Sciences, Mashad, Iran, E-mails: Mousavir{at}mums.ac.ir, Apr_mousavi{at}yahoo.com, and T_moghiman{at}yahoo.co.uk.






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Copyright © 2009 by the American Society of Tropical Medicine and Hygiene.