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Am. J. Trop. Med. Hyg., 8(1), 1959, pp. 16-19
Copyright © 1959 by The American Society of Tropical Medicine and Hygiene

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The Longevity of the Unhatched Miracidium of Schistosoma Mansoni in the Tissues of Mice1

José F. Maldonado
School of Medicine, School of Tropical Medicine, San Juan, Puerto Rico

Destruction in mice of the adult S. mansoni after 2 months of infection, by treatment with an antimonial drug, has permitted establishing 32 days as the longevity of the egg in the tissues. Evidence indicates complete development of the miracidium at oviposition. With the passage of time, there is a gradual accumulation of excretory deposits within the egg, the amber color of the egg fades, and the miracidium becomes smaller and develops deformities. The flame cells of the miracidium continue to show activity until the death of the larva. These degenerative changes are similar to changes occurring in the egg recovered in the feces of the host.


1 This investigation was supported by Research Grant No. E-942 from the National Institute of Allergy and Infectious Diseases, U. S. Public Health Service.







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Copyright © 1959 by the American Society of Tropical Medicine and Hygiene.