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Am. J. Trop. Med. Hyg., 78(5), 2008, pp. 699-701
Copyright © 2008 by The American Society of Tropical Medicine and Hygiene

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SHORT REPORT


Post-malaria Neurological Syndrome—Two Cases in Patients of African Origin

Virginie Prendki, Claire Elzière, Rémy Durand, Aicha Hamdi, Yves Cohen, Igor Onnen, AND Olivier Bouchaud*
Department of Infectious and Tropical Diseases, Hôpital Avicenne, Bobigny, France; Department of Neurology, Hôpital Avicenne, Bobigny, France, Department of Parasitology, Hôpital Avicenne, Bobigny, France; Department of Resuscitation, Hôpital Avicenne, Bobigny, France; Université Paris, Paris Nord, Bobigny, France

 

ABSTRACT

Post-malaria neurological syndrome (PMNS) defined by a post-infective encephalopathy occurring within 2 months after an episode of Plasmodium falciparum infection is still a debated entity. We describe 2 cases of PMNS in 2 patients of African origin, born and living in France. Both patients had severe P. falciparum infection, followed by PMNS. They recovered with no sequelae. These are the first-reported cases of PMNS in patients of African ethnicity and living in France.

Received September 10, 2007. Accepted for publication February 7, 2008.

* Address correspondence to Olivier Bouchaud, Department of Infectious and Tropical Diseases, Hôpital Avicenne, AP-HP, Bobigny, F-93000 France. E-mail: olivier.bouchaud{at}avc.aphp.fr

Authors’ addresses: Virginie Prendki and Olivier Bouchaud, Department of Infectious and Tropical Diseases, Hôpital Avicenne, AP-HP, Bobigny, F-93000 France. Claire Elzière and Igor Onnen, Department of Neurology, Hôpital Avicenne, AP-HP, Bobigny, F-93000 France. Rémy Durand, Department of Parasitology, Hôpital Avicenne, AP-HP, Bobigny, F-93000 France. Aicha Hamdi and Yves Cohen, Department of Resuscitation, Hôpital Avicenne, AP-HP, Bobigny, F-93000 France. Yves Cohen and Olivier Bouchaud, Université Paris, 13 Paris Nord, Bobigny, F-93017 France, Tel: 33-1-48-95-54-21, Fax: 33-1-48-95-54-28, E-mail: olivier.bouchaud{at}avc.aphp.fr.

Reprint requests: Olivier Bouchaud, Department of Infectious and Tropical Diseases, Hôpital Avicenne, AP-HP, Bobigny, F-93000 France, Tel: 33-1-48-95-54-21, Fax: 33-1-48-95-54-28, E-mail: olivier.bouchaud{at}avc.aphp.fr.






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