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In two cross-sectional surveys carried out in the rural health district of Boromo, Burkina Faso, malaria infection was evaluated in 295 pregnant women in May 2003 and 288 pregnant women in December 2003. Malaria prevalence, all P. falciparum infection, was higher in December (32.2%) than in May (11.9%) (P < 0.0001). In both surveys primigravidae had a significantly higher risk of infection than multigravidae (P < 0.0001). Such risk decreased significantly and progressively with gestational age, the highest risk being during the first trimester. Women who had not attended the antenatal clinic had also a significantly higher risk of malaria infection. Despite the high antenatal clinic attendance and the use (or misuse) of chloroquine chemoprophylaxis, malaria remains an important problem for pregnant women living in the rural district of Boromo. This requires a major effort by the health authorities to guarantee all pregnant women have access to and use preventive measures.
Received August 21, 2006. Accepted for publication January 29, 2007.
Acknowledgments: The authors thank the people of Boromo health district and particularly the participants for their cooperation. We also thank the district health authorities, the staff of the CSPS, and especially the field workers and the laboratory staff.
Financial Support: This work was supported by the European Union INCO-DEV programme (contract IC4-CT-2002-10022).
* Address correspondence to Sheick O. Coulibaly, Departement de la Biologie Médicale, Laboratoire National de Santé Publique, 09 BP 24 Ouagadougou 09, Burkina Faso. E-mail: sheickoumar{at}hotmail.com
Authors addresses: Sheick O. Coulibaly, Departement de la Biologie Médicale, Laboratoire National de Santé Publique, 09 BP 24 Ouagadougou 09, Burkina Faso. Sabine Gies and Umberto DAlessandro, Prince Leopold Institute of Tropical Medicine, Nationalestraat 155, B-2000 Antwerp, Belgium.
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