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Wilson Disease with Visceral Leishmaniasis: An Extremely Uncommon Presentation

Visceral leishmaniasis (VL), which is caused by the protozoa Leishmania donovani and transmitted by the bite of the female sand fly Phlebotomus argentipes, is common in Bihar, India. Wilson disease is an autosomal recessive disorder of copper metabolism in which copper is deposited in the brain and liver. We report a case of an extremely uncommon combination of these diseases in a patient. Treatment options for such a combination of diseases are limited and difficult.

Received December 6, 2006. Accepted for publication April 24, 2007.

Acknowledgements: We thank Sri Brijnath Prasad and Sri Naresh Kumar Sinha for assistance in preparation of the manuscript.

^* Address correspondence to K. Pandey, Rajendra Memorial Research Institute of Medical Sciences, Indian Council of Medical Research, Agamkuan, Patna 800 007, Bihar, India. E-mail: drkrishnapandey{at}yahoo.com

Authors’ address: K. Pandey, P. K. Sinha, V. N. R. Das, N. Kumar, N. Verma, S. Bimal, C. S. Lal, R. K. Topno, D. Singh, R. B. Verma, S. K. Bhattacharya, and P. Das, Rajendra Memorial of Research Institute of Medical Sciences, Indian Council of Medical Research, Agamkuan, Patna 800 007, Bihar, India.