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Am. J. Trop. Med. Hyg., 77(2), 2007, pp. 400-402
Copyright © 2007 by The American Society of Tropical Medicine and Hygiene

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Right arrow Tetanus

CASE REPORT


Tetanus-Induced Acute Kidney Injury in a Renal Transplant Recipient

Emerson Q. Lima, Ricardo G. Silva, Ida M. M. Fernandes, Mário Abbud-Filho, AND Emmanuel A. Burdmann*
Division of Nephrology, Hospital de Base, São Jose do Rio Preto Medical School, São José do Rio Preto, Brazil

 

ABSTRACT

A 48-year-old renal transplant recipient who developed tetanus 6 years after transplantation is described. His immunosuppressive protocol was mofetil mycophenolate, sirolimus, and prednisone. The patient presented symptoms of severe tetanus with autonomic dysfunction, requiring ICU care and mechanical ventilation. His clinical course was marked by development of tetanus-induced acute kidney injury and sepsis. He was discharged after 37 days of hospitalization with recovered renal function. Tetanus is a preventable disease associated with a high fatality rate. Its treatment is difficult and requires specialized and intensive care. This case highlights the crucial importance of following adequate immunization guidelines in transplant recipients.

Received February 28, 2007. Accepted for publication April 18, 2007.

Financial support: Dr. Emmanuel A. Burdmann was partially supported by a grant from CNPq, Brazil (301034/2003-6).

* Address correspondence to Emmanuel A. Burdmann, São José do Rio Preto Medical School, Av. Brigadeiro Faria Lima 5416, São José do Rio Preto, SP, Brazil, 15090-000. E-mail: burdmann{at}famerp.br

Authors’ addresses: Emerson Q. Lima, Ricardo G. Silva, Ida M.M. Fernandes, Mário Abbud-Filho, and Emmanuel A. Burdmann, Division of Nephrology, Hospital de Base, São José do Rio Preto Medical School, Av. Brigadeiro Faria Lima 5416, São José do Rio Preto, Brazil, Telephone: +55-17-32015712, Fax: +55-17-32291497, E-mails: burdmann{at}famerp.br and burdmann{at}terra.com.br.






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Copyright © 2007 by the American Society of Tropical Medicine and Hygiene.