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Am. J. Trop. Med. Hyg., 77(1), 2007, pp. 1-2
Copyright © 2007 by The American Society of Tropical Medicine and Hygiene

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EDITORIAL


Drug-Free Holidays: Pre-Travel versus During Travel Malaria Chemoprophylaxis

G. Dennis Shanks*, Alan J. Magill, David O. Freedman, Jay S. Keystone, David J. Bradley, AND Robert Steffen
Army Malaria Institute, Brisbane, Queensland, Australia; Walter Reed Army Institute of Research, Silver Spring, Maryland; University of Alabama at Birmingham, Birmingham, Alabama; The Toronto Hospital, Toronto, Ontario, Canada; London School of Hygiene and Tropical Medicine, London, United Kingdom; World Health Organization Collaborating Centre for Travelers’ Health, University of Zurich, Zurich, Switzerland

 

ABSTRACT

Although efficacious forms of malaria chemoprophylaxis currently exist, many travelers to malaria-endemic areas fail to use them effectively. We suggest that taking antimalarial medications prior to travel may prevent more malaria by improving compliance. Treatment regimens of antimalarial drugs taken prior to travel could protect persons for up to one month of exposure. We urge additional testing of pre-travel malaria chemoprophylaxis regimens.

Received March 18, 2007. Accepted for publication March 21, 2007.

Acknowledgment: The American Committee on Clinical Tropical Medicine and Travelers’ Health (ACCTMTH) assisted with publication expenses.

Disclaimer: The views in this paper are those of the authors and do not purport to reflect official policy of the U.S. Department of the Army, the Department of Defence, Australian Defence Health Service, or any existing Australian Defence Force policy. Use of medications’ proprietary names should not be interpreted as a specific endorsement of any particular company’s product.

Disclosure: All of the authors at some stage have either been members of drug advisory committees and/or received financial support for travel and/or research from pharmaceutical companies which have included GlaxoSmithKline, Pfizer, Roche, GlaxoWellcome, and SmithKline Beecham.

* Address correspondence to G. Dennis Shanks, Army Malaria Institute, Gallipoli Barracks, Enoggera, Queensland 4051, Australia. E-mail: dennis.shanks{at}defence.gov.au

Authors’ addresses: G. Dennis Shanks, Army Malaria Institute, Gallipoli Barracks, Enoggera, Brisbane, Queensland 4051, Australia, Telephone: 61-7-3332-4931, Fax: 61-7-3332 4800, E-mail: dennis.shanks{at}defence.gov.au. Alan J. Magill, Walter Reed Army Institute of Research, Silver Spring, MD 20910. David O. Freedman, University of Alabama at Birmingham, Birmingham, AL 35294. Jay S. Keystone, The Toronto Hospital, Toronto M5G 2C4, Ontario, Canada. David J. Bradley, London School of Hygiene and Tropical Medicine, London WC1E 7HT, United Kingdom, Robert Steffen, World Health Organization, Collaborating Centre for Travelers’ Health, University of Zurich, Zurich, Switzerland.




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Copyright © 2007 by the American Society of Tropical Medicine and Hygiene.