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Am. J. Trop. Med. Hyg., 76(3), 2007, pp. 603-605
Copyright © 2007 by The American Society of Tropical Medicine and Hygiene

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A CASE OF ANAPHYLACTIC REACTION TO PRAZIQUANTEL TREATMENT

CHENGHUA SHEN, MIN-HO CHOI, YOUNG MEE BAE, GUI YU, SHUHUA WANG, AND SUNG-TAE HONG*
Department of Parasitology and Tropical Medicine, and Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul, Republic of Korea; Heilongjiang Provincial Zhaoyuanxian Center for Disease Control and Prevention, Zhaoyuan, People’s Republic of China; Department of Internal Medicine, Heilongjiang Provincial Zhaoyuan People’s Hospital, Zhaoyuan, People’s Republic of China

A 35-year-old Chinese man was administered praziquantel for clonorchiasis, and 30 minutes later he experienced a sudden onset of itching urticaria over his entire body with dyspnea, palpitation, and dizziness. The patient had no recent medication history except for the praziquantel. He was diagnosed as having an anaphylactic reaction with skin eruptions induced by praziquantel. His symptoms subsided after a stomach wash and the administration of anti-anaphylactic medication in emergency department of a regional hospital in the People’s Republic of China. The immediate type of hypersensitive reaction to praziquantel is plausible, and this reaction should be considered for praziquantel therapy.

Received September 14, 2006. Accepted for publication November 28, 2006.

* Address correspondence to Sung-Tae Hong, Department of Parasitology and Tropical Medicine, and Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul 110-799, Korea. E-mail: hst{at}snu.ac.kr

Authors’ addresses: Chenghua Shen, Min-Ho Choi, Young Mee Bae, and Sung-Tae Hong, Department of Parasitology and Tropical Medicine, and Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul 110-799, Republic of Korea. Gui Yu, Heilongjiang Provincial Zhaoyuanxian Center for Disease Control and Prevention, Zhaoyuan 166500, People’s Republic of China. Shuhua Wang, Department of Internal Medicine, Heilongjiang Provincial Zhaoyuan People’s Hospital, Zhaoyuan, 166500, People’s Republic of China.

Reprint requests: Sung-Tae Hong, Department of Parasitology and Tropical Medicine, and Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul 110-799, Republic of Korea.






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