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Am. J. Trop. Med. Hyg., 75(2), 2006, pp. 324-326
Copyright © 2006 by The American Society of Tropical Medicine and Hygiene

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IS CLASSIC KAPOSI’S SARCOMA ENDEMIC IN PERU?: REPORT OF A CASE IN AN INDIGENOUS PATIENT

SALIM MOHANNA*, VICENTE MACO, ALLEN GOWN, DOMINGO MORALES, FRANCISCO BRAVO, AND EDUARDO GOTUZZO
Instituto de Medicina Tropical "Alexander von Humboldt," Universidad Peruana Cayetano Heredia, Lima, Peru; PhenoPath Laboratories, Seattle, Washington; Pathology Department, Hospital Nacional Dos de Mayo, Lima, Peru

Kaposi’s sarcoma (KS) has been classified in four clinical variants (classic or Mediterranean; endemic or African; epidemic or AIDS-related; iatrogenic or immunosuppression-related). Human herpesvirus 8 (HHV-8), has been found in all these variants. We herein discuss the unusual presentation of a 53-year-old indigenous patient with purplish-brown nodular lesions on lower extremities, and miliary tuberculosis. ELISA-HIV tests were negative and immunohistochemistry (IHC) of the tumor tissue was positive for HHV-8. This is the first reported case in which the presence of HHV-8 was evidenced by means of IHC techniques in Peru. We also review all available Peruvian literature of classic KS, a disease that has been frequently reported in indigenous population of Peru since 1968, making this country a possible endemic zone of classic KS.

Received February 8, 2006. Accepted for publication April 16, 2006.

* Address correspondence to Salim Mohanna, Av. Del Parque Norte, 775 Corpac–San Isidro, Lima, Peru. E-mail: salim17{at}yahoo.com

Authors’ addresses: Salim Mohanna, Av. Del Parque Norte, 775 Corpac–San Isidro, Lima, Peru, Telephone: 511-475-0573, E-mail: salim17{at}yahoo.com. Vicente Maco, E-mail: vicente_maco{at}hotmail.com. Allen Gown, Canal View Building 551, North 34th Street, Suite 100 Seattle, WA 98103-8675, E-mail: gown{at}phenopath.com. Domingo Morales, Av. Grau Cuadra 13, Barrios Altos, Lima, Perú. Francisco Bravo, Av. Honorio Delgado 430, Urb. Ingeniería, S.M.P., Peru, E-mail: fbravo{at}terra.com.pe. Eduardo Gotuzzo, Av. Honorio Delgado 430, Urb. Ingeniería, S.M.P., Peru, E-mail: eduardogotuzzo{at}yahoo.es.






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Copyright © 2006 by the American Society of Tropical Medicine and Hygiene.