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Am. J. Trop. Med. Hyg., 74(5), 2006, pp. 880-883
Copyright © 2006 by The American Society of Tropical Medicine and Hygiene

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SHORT REPORT


PRESCRIPTION AND ADMINISTRATION OF A 14-DAY REGIMEN OF ZINC TREATMENT FOR CHILDHOOD DIARRHEA IN MALI

PETER J. WINCH*, KATE E. GILROY, SEYDOU DOUMBIA, AMY E. PATTERSON, ZANA DAOU, SEYON COULIBALY, ERIC SWEDBERG, ROBERT E. BLACK, AND OLIVIER FONTAINE
Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Faculty of Medicine/Malaria Research and Training Center, Bamako, Mali; Save the Children, Bougouni, Mali and Westport, Connecticut; World Health Organization, Department of Child and Adolescent Health and Development, Geneva, Switzerland

 

ABSTRACT

We evaluated prescription and correct dosing of a 14-day course of dispersible zinc tablets prescribed to young children with diarrhea by community and facility workers in rural, southern Mali, West Africa. One hundred twenty-three children were followed at home on days 3 and 14 after being prescribed zinc. The age-appropriate dose of zinc was dispensed in 94% of cases. Ninety-five percent of mothers dissolved the tablet in a small amount of water and gave it with a spoon. Only eight caretakers reported problems with zinc administration: either vomiting or refusal to take the tablets. Sixty-four percent of children received the full 14-day course of treatment, and more than 89% of children were given at least a 10-day course of zinc treatment. The levels of correct administration were very good but might be lower under non-research conditions.

Received July 19, 2005. Accepted for publication November 19, 2005.

* Address correspondence to Peter J. Winch, Department of International Health, Social and Behavioral Interventions Program, Johns Hopkins Bloomberg School of Public Health, Room E5030, 615 North Wolfe Street, Baltimore, MD 21205-2103. E-mail: pwinch{at}jhsph.edu

Authors’ addresses: Peter J. Winch, Kate Gilroy, and Robert Black, Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD USA 21205-2103. Seydou Doumbia, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Dentistry, BP 1895, Bamako, Mali. Amy E. Patterson, Department of Behavioral Science and Health Education, Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA, 30322. Zana Daou and Seyon Coulibaly, Save the Children/USA, Sahel Field Office, BP 3105, Bamako, Mali. Eric Swedberg, Save the Children/USA, 54 Wilton Road, Westport, Connecticut USA 06880. Olivier Fontaine, World Health Organization, Division of Child and Adolescent Health and Development, 20 Avenue Appia, Geneva, Switzerland.




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