HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via ISI Web of Science (8) Citing Articles via Google Scholar Google Scholar Articles by COTTRELL, G. Articles by COT, M. Search for Related Content PubMed PubMed Citation Articles by COTTRELL, G. Articles by COT, M. Related Collections Malaria

IS MALARIAL PLACENTAL INFECTION RELATED TO PERIPHERAL INFECTION AT ANY TIME OF PREGNANCY?

Placental infection measured by placental smear at delivery is a standard indicator, widely used to characterize malaria infection in pregnant women. However, a single measure can hardly reflect the entire history of infection during pregnancy. To investigate the relation between this indicator and peripheral infection during pregnancy, we used data collected in a randomized trial of malaria prophylaxis in 928 pregnant women in Burkina Faso, 1987–1988, during which repeated measures of peripheral infection were taken. We analyzed placental infection using a logistic model, with two methods for handling missing data. Peripheral infection during two periods of pregnancy was significantly related to placental infection at delivery, before the fifth month: OR = 2.9 [1.3; 6.3]; after 7 months: OR = 4.9 [2.7; 8.8]). Therefore, an early peripheral infection may persist throughout gestation, and placental infection is a good indicator of the women’s parasitological status during pregnancy.

Received January 31, 2005. Accepted for publication May 26, 2005.

Acknowledgments: The authors thank Dr. Alzuma Yada, former head of the Banfora Health District, and all the midwives and pregnant women who participated in the study.

Financial support: This study was supported by a grant from the INSERM (Institut National de la Santé et de la Recherche Médicale): réseau Nord-Sud no. 486 NS2.

^* Address correspondence to Gilles Cottrell, Faculté de Pharmacie, Laboratoire de Parasitologie, 4 Avenue de l’Observatoire, 75270 Paris Cedex 06, France. E-mail: gillescottrell{at}hotmail.com

Authors’ addresses: Gilles Cottrell and Michel Cot, Faculté de Pharmacie, Laboratoire de Parasitologie, 4 Avenue de l’Observatoire, 75270 Paris Cedex 06, France; Jean-Yves Mary, INSERM U717, Université Paris 7, DBIM, Hôpital St Louis 1 av Claude Vellefaux, 75010 Paris, France; Drissa Barro, Service d’anesthésie-réanimation au Centre Hospitalier Universitaire Souro Sanou de Bobo-Dioulasso, B.P. 676 Bobo-Dioulasso, Burkina Faso.

Reprint requests: Gilles Cottrell, Faculté de Pharmacie Laboratoire de Parasitologie, 4 Avenue de l’Observatoire, 75270 Paris Cedex 06, France.

This article has been cited by other articles:

				G. COTTRELL, J.-Y. MARY, D. BARRO, and M. COT THE IMPORTANCE OF THE PERIOD OF MALARIAL INFECTION DURING PREGNANCY ON BIRTH WEIGHT IN TROPICAL AFRICA Am J Trop Med Hyg, May 1, 2007; 76(5): 849 - 854. [Abstract] [Full Text] [PDF]