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We identified 114 patients with neurocysticercosis admitted to Ben Taub General Hospital in Houston, Texas between January 1994 and June 1997. Most of these patients were born in Mexico (78%) or Central America (16%), but 6% were born in the United States. Review of neurology clinic records identified 54 patients diagnosed with neurocysticercosis, representing 2% of all neurology clinic patients and 16% of all Hispanics diagnosed with seizures. Forty-one patients were interviewed and all reported significant risk factors for infection, including ingestion of undercooked pork, pig husbandry, immigration from and frequent travel to villages in disease-endemic areas, or personal/ family history of taeniasis. Among Mexican immigrants, most were born in rural areas in Central (31%) or north central Mexico (38%). Significantly fewer of the patients were from the border states (15%). The median period from immigration to diagnosis was 58 months, but it was 28 months for the 13 patients who had not left the United States after immigration. Although neurocysticercosis is being diagnosed with increasing frequency in the United States, acquisition of infection is still strongly associated with pig husbandry in rural Latin America, with little evidence of local transmission. Even among urban immigrants to the United States and United Statesborn cases, there is close ongoing contact with disease-endemic villages.
Received November 19, 2004. Accepted for publication January 2, 2005.
Acknowledgments: We thank Jose Luis Molinari for assistance in arranging funding and Richard Armstrong for providing access to Neurology Clinic information.
Financial support: This work was supported in part by a scholarship to Yazmin Del la Garza from the Fundacion Universidad Nacional Autónoma de México.
* Address correspondence to A. Clinton White Jr., Department of Infectious Disease, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030. E-mail: arthurw{at}bcm.tmc.edu
Authors addresses: Yazmin del la Garza, Departamento de Neurologia, Instituto Nacional de Ciencias Medicas y Nuitricion Salvador Zubiran, Mexico City, Mexico. Edward A. Graviss, Department of Pathology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, Telephone: 713-798-8097, Fax: 713-798-8895. Naval G. Daver, Kimberley J. Gambarin, Wayne X. Shandera, and A. Clinton White, Jr., Department of Infectious Disease, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, Telephone: 713-798-6846, Fax: 713-798-0681, E-mail: arthurw{at}bcm.tmc.edu. Peter M. Schantz, Division of Parasitic Diseases, Centers for Disease Control and Prevention, 4770 Buford Highway, Atlanta, GA 30341, Telephone: 770-488-7767, Fax: 770-488-7761.
Reprint requests: A. Clinton White, Jr., Department of Infectious Disease, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030.
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