AJTMH ASTMH MEMBERSHIP INFORMATION: astmh@astmh.org
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 73(3), 2005, pp. 560-565
Copyright © 2005 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via ISI Web of Science (1)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by TORTEVOYE, P.
Right arrow Articles by GESSAIN, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by TORTEVOYE, P.
Right arrow Articles by GESSAIN, A.
Related Collections
Right arrow HTLV-1
Right arrow HIV
Right arrow Epidemiology

COMPARATIVE TRENDS OF SEROPREVALENCE AND SEROINCIDENCE RATES OF HUMAN T CELL LYMPHOTROPIC VIRUS TYPE I AND HUMAN IMMUNODEFICIENCY VIRUS 1 IN PREGNANT WOMEN OF VARIOUS ETHNIC GROUPS SHARING THE SAME ENVIRONMENT IN FRENCH GUIANA

PATRICIA TORTEVOYE*, PHILIPPE TUPPIN, GABRIEL CARLES, CHRISTIAN PENEAU, AND ANTOINE GESSAIN
Unité d’Epidémiologie et Physiopathologie des Virus Oncogènes, Département d’Ecosystème et Epidémiologie des Maladies Infectieuses, Institut Pasteur, Paris, France; Etablissement Français des Greffes, Paris, France; Service de Gynécologie-Obstétrique, et Service de Biologie Médicale, Centre Hospitalier Frank Joly, Saint Laurent du Maroni, Guyane Française

The objectives of this study were to compare the seroprevalence and seroincidence rates of human T cell lymphotropic virus type I (HTLV-I) and human immunodeficiency virus 1 (HIV-1) in pregnant women in several ethnic groups in French Guiana between July 1, 1991 and June 30, 2001. This study was conducted in the obstetrics unit of the hospital in Saint Laurent du Maroni in a dynamic cohort of 6,921 pregnant women with 11,679 deliveries, with new entrants each year. The overall seroprevalence of HTLV for all women differed between ethnic groups and was restricted mainly to the descendents of fugitive slaves of African origin known as Noir-Marron (181 of 4,266, 4.24%) and to Haitian women (12 of 287, 4.18%). A decrease in the biennial seroprevalence of HTLV-I was observed over time among deliveries of the Haitian women (P = 0.037), but it remained stable among Noir-Marron (P = 0.22). Fifteen of the 17 HTLV-I seroconversions occurred in the Noir-Marron, giving an incidence of 0.18 per 100 person-years. The overall seroprevalence of HIV-1 was higher in the Haitian women (10 of 293, 3.41%) than in the Noir-Marron (34 of 4,310, 0.79%) and Amerindians (4 of 552, 0.72%). A highly significant increase in the biennial seroprevalence of HIV-1 was observed among the deliveries of the Noir-Marron (P = 0.0003), but it remained stable among Haitian women (P = 0.44). Ten of the 13 HIV-1 seroconversions were observed in Noir-Marron, giving an incidence rate of 0.12 per 100 person-years. These data demonstrate the differential spreading of these two human retroviruses among pregnant women in different ethnic groups living in the same environment. While HTLV-I, which is highly endemic in groups of African origin, showed a slight decrease over time in a suspected cohort effect, HIV-1 spread rapidly in an epidemic mode, especially in the groups of the lowest socioeconomic levels.

Received October 28, 2004. Accepted for publication December 15, 2004.

Acknowledgements: We are indebted to the Service de Protection Maternelle et Infantile de la Direction Départementale des Affaires Sanitaires et Sociales–Guyane (Dr. J. Suzanon-Sankale), the Centre de Prévention et de Vaccination of St. Laurent du Maroni (Dr. M. Diop, D. Gaquière, G. Gauthier, Dr. D. Guillot, N. Joly, and Dr. Z. Tlilane), the staff of the Gynecology-Obstetrics department, especially Olivier Pavot and Diane Vernon, and the staff of the Central Laboratory of Biology of André Bouron Hospital for providing technical assistance and help in the collection of information.

* Address correspondence to Patricia Tortevoye, Unité d’Epidémiologie et Physiopathologie des Virus Oncogénes, Département d’Ecosytéme et Epidémiologie des Maladies Infectieuses, Batiment Lwoff, Institut Pasteur, 25–28 Rue du Dr. Roux, 75724, Paris, Cedex 15, France. E-mail: ptortevo{at}pasteur.fr

Authors’ addresses: Patricia Tortevoye and Antoine Gessain, Unité d’Epidémiologie et Physiopathologie des Virus Oncogènes, Département d’Ecosytème et Epidémiologie des Maladies Infectieuses, Batiment Lwoff, Institut Pasteur, 25–28 Rue du Dr. Roux, 75724, Paris, Cedex 15, France, Telephone: 33-1-45-68-89-37, Fax: 33-1-40-61-34-65, E-mails: ptortevo{at}pasteur.fr and agessain{at}pasteur.fr. Philippe Tuppin, Etablissement Français des Greffes, Paris, France. Gabriel Carles, Service de Gynécologie-Obstétrique, Centre Hospitalier Frank Joly, 97320, Saint Laurent du Maroni, Guyane Française, France. Christian Peneau, Service de Biologie Médicale, Centre Hospitalier Frank Joly, 97320, Saint Laurent du Maroni Guyane Française, France.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2005 by the American Society of Tropical Medicine and Hygiene.