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Am. J. Trop. Med. Hyg., 73(1), 2005, pp. 87-91
Copyright © 2005 by The American Society of Tropical Medicine and Hygiene

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HIGH PREVALENCE RATE OF ENTAMOEBA HISTOLYTICA ASYMPTOMATIC INFECTION IN A RURAL MEXICAN COMMUNITY

FERNANDO RAMOS, PATRICIA MORÁN, ENRIQUE GONZÁLEZ, GABRIELA GARCÍA, MANUEL RAMIRO, ALEJANDRO GÓMEZ, MARÍA DEL CARMEN GARCÍA DE LEÓN, EMMA I. MELENDRO, ALICIA VALADEZ, AND CECILIA XIMÉNEZ*
Departamento de Medicina Experimental (Department of Experimental Medicine), Facultad de Medicina (School of Medicine), UNAM (National Autonomous University of Mexico), Mexico Distrito Federal, Mexico; Hospital Regional 1° de Octubre (October 1st Regional Hospital), ISSSTE, Mexico Distrito Federal, Mexico; Coordinación de Investigación en Salud (Health Research Coordination), Centro Médico Siglo XXI (21st Century Nacional Medical Center), IMSS (Mexican Institute of Social Security), Mexico Distrito Federal, Mexico

The frequency of Entamoeba histolytica and Entamoeba dispar infection was analyzed in a rural community in the state of Morelos, Mexico, using polymerase chain reaction (PCR). Sociodemographic variables as risk factors for the infection were assessed. Results highlighted the number of individuals with intestinal parasites (43.1%) in the community, indicating extensive fecalism. A high frequency of E. histolytica asymptomatic infection, higher than E. dispar infection (13.8% versus 9.6%), was detected by PCR. Anti-amebic antibody levels (IgG) in serum and saliva (IgA) samples were not associated with E. histolytica intestinal infection. These findings suggest a predominant distribution of E. histolytica strains of low invasive potential in this community.


Received July 27, 2004. Accepted for publication January 15, 2005.

Acknowledgments: The authors would like to thank Mrs. María Elena Ortiz Tadeo and Mr. Marco Gudiño for their secretarial and computer assistance.

Financial support: Financial support was provided by grants DGSPA IN219599, DGAPA IN234202-2, and a 2001 UC MEXUS-CONACYT collaborative grant.

* Address correspondence to Cecilia Ximénez, Departamento de Medicina Experimental, Facultad de Medicina UNAM, Dr. Balmis 148, Col. Doctores, C.P. 06726, México D.F., México. E-mail: cximenez{at}servidor.unam.mx

Authors’ addresses: Fernando Ramos, Patricia Morán, Enrique González, Gabriela García, Manuel Ramiro, María del Carmen García de León, Emma I Melendro, Alicia Valadez, and Cecilia Ximénez, Departamento de Medicina Experimental, Facultad de Medicina UNAM, Dr. Balmis 148, Col. Doctores, C.P. 06726, México D.F., México. Alejandro Gómez, Coordinación de Investigación en Salud, IMSS, Centro Médico Siglo XXI, Av. Cuauhtemoc 330, Col. Doctores, C.P. 06725, México D.F., México.

Reprint requests: Dra. Cecilia Ximénez, Departamento de Medicina Experimental, Facultad de Medicina, UNAM, Dr. Balmis 148, Col. Doctores, CP 06726, México D.F., México. Telephone: +5255-5623 2666, Fax: +5255-5623 2669, E-mail: cximenez{at}servidor.unam.mx.




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Copyright © 2005 by the American Society of Tropical Medicine and Hygiene.