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Am. J. Trop. Med. Hyg., 72(1), 2005, pp. 10-12
Copyright © 2005 by The American Society of Tropical Medicine and Hygiene

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SHORT REPORT: PROSPECTIVE EVALUATION OF A MULTI-TEST STRIP FOR THE DIAGNOSES OF SCRUB AND MURINE TYPHUS, LEPTOSPIROSIS, DENGUE FEVER, AND SALMONELLA TYPHI INFECTION

GEORGE WATT, KRISADA JONGSAKUL, RONNATRAI RUANGVIRAYUTH, PACHAREE KANTIPONG, AND KHACHORNSAKDI SILPAPOJAKUL
Department of Retrovirology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand; Department of Medicine, Mae Sot Hospital, Mae Sot, Thailand; Department of Medicine, Chiangrai Regional Hospital, Chiangrai, Thailand; Department of Medicine, Prince of Songkla University, Hat Yai, Thailand

A multi-test strip dotblot immunoassay for the diagnosis of typhoid fever, scrub typhus, murine typhus, dengue virus infection and leptospirosis was evaluated in Thai adults presenting to hospital with acute, undifferentiated fever. The kit gave multiple positive test results in 33 of 36 patients with defined infections and was therefore not a useful admission diagnostic tool.

Received June 15, 2004. Accepted for publication July 23, 2004.

Acknowledgments: We thank the Virology Department of the Armed Forces Institute of Research Sciences for performing dengue virus serodiagnosis and the Departments of Internal Medicine at the three study hospitals for their support.

Authors’ addresses: George Watt, Mahidol-Maryland Tropical Disease Research Program, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand 10400, Telephone: 66-2-354-1754, Fax: 66-2-354-1792, E-mail: gwattth{at}yahoo.com. Krisada Jongsakul, Department of Immunology and Medicine, Armed Forces Institute of Research Sciences, Bangkok 10400, Thailand, Telephone: 66-2-644-5775, Fax: 66-2-644-4784, E-mail: krisadaj{at}afrims.org. Ronnatrai Ruangvirayuth, Department of Medicine, Mae Sot Hospital, Mae Sot 63110, Thailand, Telephone: 66-55-531-229, Fax: 66-55-533-046, E-mail: ronnatrai{at}hotmail.com. Pacharee Kantipong, Department of Medicine, Chiangrai Regional Hospital, Chiangrai 57000, Thailand, Telephone: 66-1-885-9195, Fax: 66-53-713-044, E-mail: pachareek{at}hotmail.com. Khachornsakdi Silpapojakul, Department of Medicine, Faculty of Medicine, Prince of Songkla University, Had-yai, Songkla 90110, Thailand 90110, Telephone: 66-74-429-385, Fax: 66- 74-212-900, E-mail: skhachorn{at}medicine.psu.ac.th.

Reprint requests: George Watt, Mahidol-Maryland University Tropical Medicine Research Program, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand 10400.




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Copyright © 2005 by the American Society of Tropical Medicine and Hygiene.