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Am. J. Trop. Med. Hyg., 71(5), 2004, pp. 552-553
Copyright © 2004 by The American Society of Tropical Medicine and Hygiene

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Right arrow Schistosomiasis

SYMPTOMS OF INTESTINAL SCHISTOSOMIASIS PRESENTING DURING TREATMENT OF LARGE B CELL LYMPHOMA

MARTIN MONTES, A. CLINTON WHITE, JR., AND DIMITRIOS P. KONTOYIANNIS
Department of Internal Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, Texas; Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M.D. Anderson Cancer Center, Houston, Texas

We report a case of chronic intestinal schistosomiasis presenting in a previously asymptomatic 34-year-old woman from Saudi Arabia with large B cell lymphoma. The patient presented with abdominal pain, constipation, recurrent rectal bleeding, and persistent mild eosinophilia during chemotherapy. Stools were repeatedly negative for parasite ova, but duodenal and colonic biopsies demonstrated Schistosoma eggs and eosinophilic granulomatous inflammation. Immunosuppressed patients with schistosomiasis may have diminished egg excretion. Diagnosis requires a high index of suspicion since stool test results may be negative and intestinal biopsies may be needed to make the diagnosis.

Received March 17, 2004. Accepted for publication May 28, 2004.

Authors’ addresses: Martin Montes, Department of Internal Medicine, Infectious Diseases Section, Baylor College of Medicine, 1 Baylor Plaza, Room 535E, Houston TX, 77030, Telephone: 713-798-6846, Fax: 713-790-0681, E-mail: montes{at}bcm.tmc.edu. A. Clinton White Jr., Department of Internal Medicine, Infectious Diseases Section, Baylor College of Medicine, 1 Baylor Plaza, Room 535E, Houston, TX 77030, Telephone: 713-798-5246, Fax: 713-790-0681, E-mail: arthurw{at}bcm.tmc.edu. Dimitrios P. Kontoyiannis, Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M.D. Anderson Cancer Center, Box 0402, 1515 Holcombe Boulevard, Houston, TX 77030, Telephone: 713-792-0826, E-mail: dkontoyi{at}mdanderson.org.






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Copyright © 2004 by the American Society of Tropical Medicine and Hygiene.