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The Effect of Viable Bacteria on the Capacity of a Strain of Large-Race Entamoeba Histolytica to Produce Abscesses in the Hamster Liver¹

Lesions were produced in hamster livers by direct inoculation with suspensions of E. histolytica (strain K-9) prepared from S-F medium. The presence of viable bacteria (streptobacillus) in the inoculum resulted in a higher per cent of positive lesions than occurred with inocula from which bacteria were not demonstrated. The addition of large numbers of bacteria (streptobacillus) to the inoculum did not increase the percentage of positive lesions.

¹ This investigation was supported by a grant (E-499C4) from the Microbiological Institute of the National Institutes of Health, Public Health Service.