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Am. J. Trop. Med. Hyg., 69(3), 2003, pp. 341-343
Copyright © 2003 by The American Society of Tropical Medicine and Hygiene

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EOSINOPHILIC MENINGOENCEPHALITIS DUE TO TOXOCARA CANIS: CASE REPORT AND REVIEW OF THE LITERATURE

JOSE E. VIDAL, JAQUES SZTAJNBOK, AND ANTONIO CARLOS SEGURO
Unidade de Terapia Intensiva do Instituto de Infectologia Emílio Ribas, São Paulo, Brazil; Laboratório de Investigação Médica, Hospital das Clínicas, Faculdade de Medicina da Universidade São Paulo, São Paulo, Brazil

Toxocariasis is usually manifested as visceral larva migrans. Nervous system involvement is a rare complication. In this report, we describe one case of meningoencephalitis due to Toxocara canis and review the literature. We report a previously healthy two-year-old boy who was admitted after 24 hours of severe neurologic symptoms with marked eosinophilic pleocytosis in the cerebrospinal fluid and a single subcortical lesion detected by cerebral magnetic resonance imaging. Both serum and spinal fluid tested positive for T. canis. Initial treatment with thiabendazole was ineffective. After marked improvement in clinical and laboratory results were achieved using albendazole and corticosteroids, the child was discharged.

Received March 26, 2003. Accepted for publication July 7, 2003.

Financial support: This work was supported in part by the Centro de Estudos Emílio Ribas.

Authors’ address: José E. Vidal, Jaques Sztajnbok, and Antonio Carlos Seguro, Unidade de Terapia Intensiva, Instituto de Infectologia Emílio Ribas, Av. Dr. Arnaldo 165, São Paulo, SP 01246-900, Brazil.

Reprint requests: José E. Vidal, Unidade de Terapia Intensiva, Instituto de Infectologia Emílio Ribas, Av. Dr. Arnaldo 165, São Paulo, SP 01246-900, Brazil, Telephone: 55-11-9588-8756, Fax: 55-11-3088-3602, E-mail: jbermudez{at}emilioribas.sp.gov.br.




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