AJTMH ASTMH Job Mart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 66(6), 2002, pp. 686-691
Copyright © 2002 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gerardin, P
Right arrow Articles by Imbert, P
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gerardin, P
Right arrow Articles by Imbert, P
Related Collections
Right arrow Malaria
American Journal of Tropical Medicine and Hygiene, Vol 66, Issue 6, 686-691
Copyright © 2002 by American Society of Tropical Medicine and Hygiene

Research Articles


Prognostic value of thrombocytopenia in African children with falciparum malaria

P Gerardin, C Rogier, AS Ka, P Jouvencel, V Brousse, and P Imbert

Thrombocytopenia is a common finding in malaria, but its prognostic value has not been addressed in children. The relationship between thrombocytopenia (platelet count < 100,000/mm3 on admission) and severity and outcome was investigated prospectively in children hospitalized with falciparum malaria in Dakar, Senegal, an area that is hypoendemic for malaria. Of 288 falciparum cases, 215 matched the 2000 World Health Organization definition of severe malaria. Median platelet counts were lower (98,000/mm3 versus 139,000/mm3; P < 0.02) among severe cases than in mild cases, and in children who died than among those who recovered (68,500/mm3 versus 109,000/mm3; P < 0.002). In severe cases, children presenting with a platelet count < 100,000/mm3 were more likely to die (odds ratio [OR] = 6.31, 95% confidence interval [CI] = 2.0-26.0). Moreover, multivariate analysis identified thrombocytopenia as an independent predictor of death (OR = 13.3, 95% CI = 3.2-55.1). Our data show an association between thrombocytopenia and either severity or prognosis in childhood falciparum malaria.


This article has been cited by other articles:


Home page
 Am J Trop Med HygHome page
C. CASALS-PASCUAL, O. KAI, C. R. J. C. NEWTON, N. PESHU, and D. J. ROBERTS
THROMBOCYTOPENIA IN FALCIPARUM MALARIA IS ASSOCIATED WITH HIGH CONCENTRATIONS OF IL-10.
Am J Trop Med Hyg, September 1, 2006; 75(3): 434 - 436.
[Abstract] [Full Text] [PDF]

Home page
 Arch. Dis. Child.Home page
C Rogier, P Gerardin, and P Imbert
Thrombocytopenia is predictive of lethality in severe childhood falciparum malaria
Arch. Dis. Child., August 1, 2004; 89(8): 795 - 796.
[Full Text] [PDF]

Home page
 Am J Trop Med HygHome page
L. M. ERHART, K. YINGYUEN, N. CHUANAK, N. BUATHONG, A. LAOBOONCHAI, R. S. MILLER, S. R. MESHNICK, R. A. GASSER JR., and C. WONGSRICHANALAI
HEMATOLOGIC AND CLINICAL INDICES OF MALARIA IN A SEMI-IMMUNE POPULATION OF WESTERN THAILAND
Am J Trop Med Hyg, January 1, 2004; 70(1): 8 - 14.
[Abstract] [Full Text] [PDF]

Home page
 Am J Trop Med HygHome page
F. MOERMAN, B. COLEBUNDERS, and U. D'ALESSANDRO
Thrombocytopenia in African children can predict the severity of malaria caused by Plasmodium falciparum and the prognosis of the disease.
Am J Trop Med Hyg, April 1, 2003; 68(4): 379 - 379.
[Full Text] [PDF]

Home page
 Am J Trop Med HygHome page
P. IMBERT, C. ROGIER, and P. GERARDIN
LETTER TO THE EDITOR
Am J Trop Med Hyg, April 1, 2003; 68(4): 380 - 381.
[Full Text] [PDF]

Home page
 Am J Trop Med HygHome page
S. LADHANI and C. R. J. C. NEWTON
Plasmodium falciparum malaria in a hypoendemic region in Senegal.
Am J Trop Med Hyg, April 1, 2003; 68(4): 379 - 380.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2002 by the American Society of Tropical Medicine and Hygiene.