AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 66(6), 2002, pp. 649-652
Copyright © 2002 by The American Society of Tropical Medicine and Hygiene

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American Journal of Tropical Medicine and Hygiene, Vol 66, Issue 6, 649-652
Copyright © 2002 by American Society of Tropical Medicine and Hygiene

Research Articles


Assessing the Parasight-F test in northeastern Papua, Indonesia, an area of mixed Plasmodium falciparum and Plasmodium vivax transmission

WR Taylor, H Widjaja, H Basri, DJ Fryauff, C Ohrt, Taufik, E Tjitra, SL Hoffman, S Baso, and TL Richie

User-friendly, reliable, and inexpensive methods for diagnosing malaria are needed at the primary health care level. During a randomized treatment trial, the Parasight-F test was assessed on days 0, 3, 7, and 28 against standard light microscopy of Giemsa-stained thick blood smears for diagnosing Plasmodium falciparum parasitemia in patients with P. falciparum (n = 84) or P. vivax (n = 59) malaria. The median P. falciparum parasite count on day 0 was 2,373/microL (range = 20-74,432/microL). At the start of treatment, the Parasight-F test had a sensitivity of 95.2% (80 of 84; 95% confidence interval [CI] = 88.2-98.7), and a specificity of 94.9% (56 of 59; 95% CI = 85.8-98.9). On day 7, this test showed false-positive results in 17 (16.3%) of 104 patients (95% CI = 9.8-24.9). The Parasight-F test performed well when compared with light microscopy in detecting P. falciparum parasitemia in patients presenting with clinical malaria. However, the high false-positive rate on day 7 limits its use for patient follow-up.


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C. WONGSRICHANALAI, I. AREVALO, A. LAOBOONCHAI, K. YINGYUEN, R. S. MILLER, A. J. MAGILL, J. R. FORNEY, and R. A. GASSER JR.
RAPID DIAGNOSTIC DEVICES FOR MALARIA: FIELD EVALUATION OF A NEW PROTOTYPE IMMUNOCHROMATOGRAPHIC ASSAY FOR THE DETECTION OF PLASMODIUM FALCIPARUM AND NON-FALCIPARUM PLASMODIUM
Am J Trop Med Hyg, July 1, 2003; 69(1): 26 - 30.
[Abstract] [Full Text] [PDF]


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