AJTMH ASTMH Job Mart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 65(5), 2001, pp. 631-636
Copyright © 2001 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Beck, S
Right arrow Articles by Stark, K
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Beck, S
Right arrow Articles by Stark, K
Related Collections
Right arrow Travel Medicine
Right arrow Malaria
American Journal of Tropical Medicine and Hygiene, Vol 65, Issue 5, 631-636
Copyright © 2001 by American Society of Tropical Medicine and Hygiene

Research Articles


Multiplicity of Plasmodium falciparum infection in pregnancy

S Beck, FP Mockenhaupt, U Bienzle, TA Eggelte, WN Thompson, and K Stark

Little is known about the distribution and disease association of multiple Plasmodium falciparum infections in pregnant women. Genotyping of the merozoite surface protein-1 region was performed in 332 P. falciparum infected pregnant women in Ghana, and clinical and epidemiologic data were obtained. Overall, 68% of the women were infected with more than one strain (mean number of strains per carrier = 2.9). The multiplicity of infection decreased significantly with an increasing number of pregnancies, and infection with multiple P. falciparum strains was significantly associated with anemia. In logistic regression, women infected with four or more strains were 2.3 times more likely to be anemic than women harboring fewer strains. This association, however, was only observed in women with up to three pregnancies. The results suggest that with increasing gravidity and subsequent infections with multiple strains effective immune mechanisms against more and more strains develop. In pregnant women, the multiplicity of infection may be an important factor for the acquisition and maintenance of immunity against malaria.


This article has been cited by other articles:


Home page
 Antimicrob. Agents Chemother.Home page
J. J. Kwiek, A. P. Alker, E. C. Wenink, M. Chaponda, L. V. Kalilani, and S. R. Meshnick
Estimating True Antimalarial Efficacy by Heteroduplex Tracking Assay in Patients with Complex Plasmodium falciparum Infections
Antimicrob. Agents Chemother., February 1, 2007; 51(2): 521 - 527.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Microbiol.Home page
S. Jafari-Guemouri, N. T. Ndam, G. Bertin, E. Renart, S. Sow, J.-Y. Le Hesran, and P. Deloron
Demonstration of a High Level of Parasite Population Homology by Quantification of Plasmodium falciparum Alleles in Matched Peripheral, Placental, and Umbilical Cord Blood Samples
J. Clin. Microbiol., June 1, 2005; 43(6): 2980 - 2983.
[Abstract] [Full Text] [PDF]

Home page
 Am J Trop Med HygHome page
A. WALKER-ABBEY, R. R. T. DJOKAM, A. ENO, R. F. G. LEKE, V. P. K. TITANJI, J. FOGAKO, G. SAMA, L. H. THUITA, E. BEARDSLEE, G. SNOUNOU, et al.
MALARIA IN PREGNANT CAMEROONIAN WOMEN: THE EFFECT OF AGE AND GRAVIDITY ON SUBMICROSCOPIC AND MIXED-SPECIES INFECTIONS AND MULTIPLE PARASITE GENOTYPES
Am J Trop Med Hyg, March 1, 2005; 72(3): 229 - 235.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
D. W. Taylor, A. Zhou, L. E. Marsillio, L. W. Thuita, E. B. Leke, O. Branch, D. C. Gowda, C. Long, and R. F. G. Leke
Antibodies That Inhibit Binding of Plasmodium falciparum-Infected Erythrocytes to Chondroitin Sulfate A and to the C Terminus of Merozoite Surface Protein 1 Correlate with Reduced Placental Malaria in Cameroonian Women
Infect. Immun., March 1, 2004; 72(3): 1603 - 1607.
[Abstract] [Full Text] [PDF]

Home page
 Am J Trop Med HygHome page
F. O. TER KUILE, D. J. TERLOUW, P. A. PHILLIPS-HOWARD, W. A. HAWLEY, J. F. FRIEDMAN, S. K. KARIUKI, Y. P. SHI, M. S. KOLCZAK, A. A. LAL, J. M. VULULE, et al.
REDUCTION OF MALARIA DURING PREGNANCY BY PERMETHRIN-TREATED BED NETS IN AN AREA OF INTENSE PERENNIAL MALARIA TRANSMISSION IN WESTERN KENYA
Am J Trop Med Hyg, April 1, 2003; 68(90040): 50 - 60.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2001 by the American Society of Tropical Medicine and Hygiene.