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Am. J. Trop. Med. Hyg., 65(5), 2001, pp. 599-602
Copyright © 2001 by The American Society of Tropical Medicine and Hygiene

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American Journal of Tropical Medicine and Hygiene, Vol 65, Issue 5, 599-602
Copyright © 2001 by American Society of Tropical Medicine and Hygiene

Research Articles


Comparison of methods for the rapid laboratory assessment of children with malaria

T Planche, S Krishna, M Kombila, K Engel, JF Faucher, E Ngou-Milama, and PG Kremsner

Rapid diagnosis and accurate quantification of Plasmodium falciparum parasitemia are important for the management of malaria. The assessment of disease severity also depends on evaluation of metabolic indexes such as blood glucose and lactate concentrations. Here we describe an accurate and rapid alternative to conventional thick film examination (Lambarene method). We also assess near-patient methods for measuring blood glucose (OneTouch) and lactate (Accusport). The accuracy of the Lambarene method is similar to that of thin films. Results from the OneTouch glucose meter also are in good agreement with a YSI 2300 reference meter. Overall, the Accusport lactate meter agrees poorly with the YSI 2300 reference meter. However, the sensitivity and specificity to detect hyperlactatemia (blood lactate > or = 5 mmol/L) are 0.94 and 0.98, respectively.


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