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Am. J. Trop. Med. Hyg., 65(1), 2001, pp. 15-18
Copyright © 2001 by The American Society of Tropical Medicine and Hygiene

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American Journal of Tropical Medicine and Hygiene, Vol 65, Issue 1, 15-18
Copyright © 2001 by American Society of Tropical Medicine and Hygiene

Research Articles


Protection of pigs with cysticercosis from further infections after treatment with oxfendazole

AE Gonzalez, C Gavidia, N Falcon, T Bernal, M Verastegui, HH Garcia, RH Gilman, and VC Tsang

Cysticercosis, the infection by the larvae of Taenia solium, is a major cause of acquired epilepsy in the world; it also causes significant economic loss because of contaminated pork. This disease is endemic in most developing countries and no control strategy has yet been proven efficient and sustainable. To further evaluate the full potential of single-dose oxfendazole treatment for pigs as a control measure, 20 pigs with cysticercosis were treated with oxfendazole and later matched with 41 naive pigs and exposed to a natural challenge in a hyperendemic area. New infections were found by serologic testing in 15 of the 32 controls (47%), and by the presence of cysts at necropsy in 12 of them (37%). Only minute residual scars were detected in the carcasses of oxfendazole-treated pigs. Pigs with cysticercosis, once treated with oxfendazole, are protected from new infections for at least three months.


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S. HANDALI, A. E. GONZALEZ, K. HANCOCK, H. H. GARCIA, J. M. ROBERTS, R. H. GILMAN, and V. C. W. TSANG
PORCINE ANTIBODY RESPONSES TO TAENIA SOLIUM ANTIGENS RGP50 AND STS18VAR1
Am J Trop Med Hyg, September 1, 2004; 71(3): 322 - 326.
[Abstract] [Full Text] [PDF]

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M. VERASTEGUI, R. H. GILMAN, H. H. GARCIA, A. E. GONZALEZ, Y. ARANA, C. JERI, I. TUERO, C. M. GAVIDIA, M. LEVINE, and V. C. W. TSANG
PREVALENCE OF ANTIBODIES TO UNIQUE TAENIA SOLIUM ONCOSPHERE ANTIGENS IN TAENIASIS AND HUMAN AND PORCINE CYSTICERCOSIS
Am J Trop Med Hyg, October 1, 2003; 69(4): 438 - 444.
[Abstract] [Full Text] [PDF]


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Copyright © 2001 by the American Society of Tropical Medicine and Hygiene.