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Kits for self-diagnosis of malaria by travelers in remote areas have been advocated. Antigen-capture test cards work reliably in the laboratory, but there is limited data regarding self-testing by ill patients. One hundred and fifty-three symptomatic patients presenting for a malaria test attempted self-diagnosis using these kits. Nine percent failed to perform a valid test. Against blood-film proven malaria, specificity was 97% (95% confidence intervals [CI] 93-99%) and sensitivity 95% (95% CI 74-99%). Although these results are encouraging, technical problems need to be addressed and test sensitivity proven by additional field-testing before this technology can be marketed to travelers.
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L. H. Chen, M. E. Wilson, and P. Schlagenhauf Prevention of malaria in long-term travelers. JAMA, November 8, 2006; 296(18): 2234 - 2244. [Abstract] [Full Text] [PDF] |
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A. Moody Rapid Diagnostic Tests for Malaria Parasites Clin. Microbiol. Rev., January 1, 2002; 15(1): 66 - 78. [Abstract] [Full Text] [PDF] |
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