| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
In a prospective study in Barbados between 1979 and 1989, 321 cases were diagnosed in 638 patients presenting at a hospital with symptoms of leptospirosis. Initial diagnosis was based on patient history and characteristic signs and symptoms. In 92 cases (29%), diagnosis was confirmed by isolation of organisms from the blood, urine, or dialysate fluid; in the remaining 229 cases (71%) diagnosis was confirmed by serology alone. Results of an IgM-ELISA and microscopic agglutination test (MAT) in cases with isolates and in non-leptospirosis cases were used to assess the sensitivity and specificity of the tests. The sensitivity of IgM detection by ELISA was 52% in the first acute-phase specimen, increasing to 89% and 93% in the second acute-phase and convalescent specimens, respectively. The specificity of the IgM-ELISA was high (> or = 94%) in all specimens. The sensitivity of the MAT was low (30%) in the first acute-phase specimen, increasing to 63% in the second acute-phase specimen and 76% in the convalescent specimen. The specificity of the MAT was > or = 97% in all specimens.
This article has been cited by other articles:
|
|
 |
|
  G. Doungchawee, U. Kositanont, A. Niwetpathomwat, T. Inwisai, P. Sagarasaeranee, and D. A. Haake Early Diagnosis of Leptospirosis by Immunoglobulin M Immunoblot Testing Clin. Vaccine Immunol., March 1, 2008; 15(3): 492 - 498. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Sharma, U. Tuteja, R. Khushiramani, J. Shukla, and H. V. Batra Application of rapid dot-ELISA for antibody detection of leptospirosis J. Med. Microbiol., June 1, 2007; 56(6): 873 - 874. [Full Text] [PDF]
|
|
|
|
 |
|
 J. Croda, J. G. R. Ramos, J. Matsunaga, A. Queiroz, A. Homma, L. W. Riley, D. A. Haake, M. G. Reis, and A. I. Ko Leptospira Immunoglobulin-Like Proteins as a Serodiagnostic Marker for Acute Leptospirosis J. Clin. Microbiol., May 1, 2007; 45(5): 1528 - 1534. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Hull-Jackson, M. B. Glass, M. D. Ari, S. L. Bragg, S. L. Branch, C. U. Whittington, C. N. Edwards, and P. N. Levett Evaluation of a commercial latex agglutination assay for serological diagnosis of leptospirosis. J. Clin. Microbiol., May 1, 2006; 44(5): 1853 - 1855. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Yitzhaki, A. Barnea, A. Keysary, and E. Zahavy New Approach for Serological Testing for Leptospirosis by Using Detection of Leptospira Agglutination by Flow Cytometry Light Scatter Analysis J. Clin. Microbiol., April 1, 2004; 42(4): 1680 - 1685. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. G. Priya, K. Bhavani, S. R. Rathinam, and V. R. Muthukkaruppan Identification and evaluation of LPS antigen for serodiagnosis of uveitis associated with leptospirosis J. Med. Microbiol., August 1, 2003; 52(8): 667 - 673. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. D. Bajani, D. A. Ashford, S. L. Bragg, C. W. Woods, T. Aye, R. A. Spiegel, B. D. Plikaytis, B. A. Perkins, M. Phelan, P. N. Levett, et al. Evaluation of Four Commercially Available Rapid Serologic Tests for Diagnosis of Leptospirosis J. Clin. Microbiol., February 1, 2003; 41(2): 803 - 809. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Flannery, D. Costa, F. P. Carvalho, H. Guerreiro, J. Matsunaga, E. D. Da Silva, A. G. P. Ferreira, L. W. Riley, M. G. Reis, D. A. Haake, et al. Evaluation of Recombinant Leptospira Antigen-Based Enzyme-Linked Immunosorbent Assays for the Serodiagnosis of Leptospirosis J. Clin. Microbiol., September 1, 2001; 39(9): 3303 - 3310. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. N. Levett Leptospirosis Clin. Microbiol. Rev., April 1, 2001; 14(2): 296 - 326. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. N. Levett, S. L. Branch, C. U. Whittington, C. N. Edwards, and H. Paxton Two Methods for Rapid Serological Diagnosis of Acute Leptospirosis Clin. Vaccine Immunol., March 1, 2001; 8(2): 349 - 351. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
