AJTMH HINARI
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 60(1), 1999, pp. 7-13
Copyright © 1999 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Williams, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Williams, J.
Related Collections
Right arrow Malaria
Right arrow Plasmodium
American Journal of Tropical Medicine and Hygiene, Vol 60, Issue 1, 7-13
Copyright © 1999 by American Society of Tropical Medicine and Hygiene

Research Articles


Stimulation of Plasmodium falciparum gametocytogenesis by conditioned medium from parasite cultures

JL Williams

Plasmodium falciparum gametocyte development was examined in erythrocyte monolayer cultures prepared with Cell-Tak, a cell and tissue adhesive. The monolayers, which were stable for up to 10 days in culture, supported multiple cycles of asexual growth and the development of clusters of stage IV gametocytes. Small numbers of chicken erythrocytes incorporated into the monolayers served as internal reference standards for parasite counts. This permitted quantitative assessment of gametocyte formation under different culture conditions. Gametocyte formation was limited in monolayers grown in standard culture medium but it increased slightly in monolayers cocultured with suspensions of parasitized erythrocytes. The number of gametocytes increased significantly in monolayers grown in parasite-conditioned medium. In both cases the changes resulted from increased numbers of stage II and III gametocytes in the monolayers. These results suggest that parasite conditioned medium contains a factor(s) that stimulates sexual development.


This article has been cited by other articles:


Home page
 J. Biol. Chem.Home page
R. Ranjan, A. Ahmed, S. Gourinath, and P. Sharma
Dissection of Mechanisms Involved in the Regulation of Plasmodium falciparum Calcium-dependent Protein Kinase 4
J. Biol. Chem., May 29, 2009; 284(22): 15267 - 15276.
[Abstract] [Full Text] [PDF]

Home page
 Eukaryot CellHome page
S. Sharp, T. Lavstsen, Q. L. Fivelman, M. Saeed, L. McRobert, T. J. Templeton, A. T. R. Jensen, D. A. Baker, T. G. Theander, and C. J. Sutherland
Programmed Transcription of the var Gene Family, but Not of stevor, in Plasmodium falciparum Gametocytes
Eukaryot. Cell, August 1, 2006; 5(8): 1206 - 1214.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
T. Furuya, J. Mu, K. Hayton, A. Liu, J. Duan, L. Nkrumah, D. A. Joy, D. A. Fidock, H. Fujioka, A. B. Vaidya, et al.
Disruption of a Plasmodium falciparum gene linked to male sexual development causes early arrest in gametocytogenesis
PNAS, November 15, 2005; 102(46): 16813 - 16818.
[Abstract] [Full Text] [PDF]

Home page
 Am J Trop Med HygHome page
M. DYER and K. P. DAY
REGULATION OF THE RATE OF ASEXUAL GROWTH AND COMMITMENT TO SEXUAL DEVELOPMENT BY DIFFUSIBLE FACTORS FROM IN VITRO CULTURES OF PLASMODIUM FALCIPARUM
Am J Trop Med Hyg, April 1, 2003; 68(4): 403 - 409.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
L. Cui, Q. Fan, and J. Li
The malaria parasite Plasmodium falciparum encodes members of the Puf RNA-binding protein family with conserved RNA binding activity
Nucleic Acids Res., November 1, 2002; 30(21): 4607 - 4617.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1999 by the American Society of Tropical Medicine and Hygiene.