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Am. J. Trop. Med. Hyg., 6(5), 1957, pp. 894-897
Copyright © 1957 by The American Society of Tropical Medicine and Hygiene

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The Anthelmintic Effect of Dithiazanine1 in Experimental Animals

Max C. McCowen, Maurice E. Callender AND Milo C. Brandt
The Lilly Research Laboratories, Indianapolis, Indiana

A new anthelmintic compound, dithiazanine (3,3'diethylthiadicarbocyanine iodide), was found to be highly effective by oral administration against pinworms in mice, ascarids, hookworms, and whipworms in dogs, as well as ascarids and hookworms in cats.

Further investigations are necessary to determine if dithiazanine is effective in the treatment of such human helminthic diseases as ascariasis, oxyuriasis, trichuriasis and strongyloidiasis.


1 Dithiasanine, Lilly, is the generic name for 3,3' diethylthiadicarbocyanine iodide.






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Copyright © 1957 by the American Society of Tropical Medicine and Hygiene.