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Needle Biopsy in the Etiologic Diagnosis of Splenomegaly^*

Needle biopsy of the spleen was performed in 55 cases of splenomegaly in Egypt to establish a diagnosis impossible by clinical examination alone. Cores of tissue thus obtained were sectioned and stained, providing a basis for differentiating chronic congestive splenomegaly associated with schistosomiasis from other etiologic types, which is hardly possible with aspirated material. The pathological changes in 44 cases of congestive splenomegaly are described, and correlated in 22 cases with needle biopsy material from the liver. Needle biopsy may be indicated in other types of splenomegaly, since the procedure proved to be without mortality or complications in this series of cases.

^* The opinions or assertions contained herein are the private ones of the authors and are not to be construed as official or reflecting the views of the Navy Department or the naval service at large.