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Am. J. Trop. Med. Hyg., 58(6), 1998, pp. 821-823
Copyright © 1998 by The American Society of Tropical Medicine and Hygiene

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American Journal of Tropical Medicine and Hygiene, Vol 58, Issue 6, 821-823
Copyright © 1998 by American Society of Tropical Medicine and Hygiene

Research Articles


Excessive fibrinolysis: the coagulopathy following Merrem's hump-nosed viper (Hypnale hypnale) bites

AP Premawardena, SL Seneviratne, SB Gunatilake, and HJ de Silva

In 56 patients with proven hump-nosed viper (Hypnale hypnale) bites, 12 (21.4%) developed continued oozing of blood from the site of the bite and a prolonged clotting time. Further investigations showed low fibrinogen levels and increased fibrinogen degradation products in plamsa. The bleeding time, platelet count, prothrombin time, and partial thromboplastin time with kaolin were normal. The bite of this snake can be complicated with a coagulopathy in which excessive fibrinolysis seems to be the main abnormality.




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Copyright © 1998 by the American Society of Tropical Medicine and Hygiene.