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Am. J. Trop. Med. Hyg., 51(2), 1994, pp. 180-182
Copyright © 1994 by The American Society of Tropical Medicine and Hygiene

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Brain Abscess due to Infection with Entamoeba Histolytica

Kenji Ohnishi, Misako Murata, Hirooki Kojima, Nobuhiko Takemura, Tomio Tsuchida AND Hiroshi Tachibana
Departments of Infectious Diseases and Neurosurgery, Tokyo Metropolitan Bokutoh General Hospital, Tokyo, Japan; Department of Infectious Diseases, Tokai University School of Medicine, Kanagawa, Japan

We successfully treated a serious case of Entamoeba histolytica infection showing brain abscess, meningitis, and liver abscess by oral administration of metronidazole, intramuscular injection of dehydroernetine, and drainage of the brain abscess. The diagnosis of amebic brain abscess was based on a combination of clinical symptoms and signs, computed tomography and magnetic resonance imaging findings, a positive serologic test result for E. histolytica, a dramatic response to anti-amebic drugs after an ineffective therapeutic history with antibacterial drugs, and application of the polymerase chain reaction method.






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Copyright © 1994 by the American Society of Tropical Medicine and Hygiene.