AJTMH HINARI
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 50(2), 1994, pp. 145-151
Copyright © 1994 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Boher, Y.
Right arrow Articles by Tapia, F. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Boher, Y.
Right arrow Articles by Tapia, F. J.

Enumeration of Selected Leukocytes in the Small Intestine of BALB/c Mice Infected with Cryptosporidium Parvum

Y. Boher, I. Perez-Schael, G. Caceres-Dittmar, G. Urbina, R. Gonzalez, G. Kraal AND F. J. Tapia
Instituto de Biomedicina, Universidad Central de Venezuela, Caracas, Venezuela; Department of Histology, Free University of Amsterdam, Amsterdam, The Netherlands

Neonatal, suckling BALB/c mice inoculated with Cryptosporidium parvum produce an infection characterized by continuous shedding of oocysts that spontaneously clears by the time the animals are three weeks of age. Neonatal mice were used to characterize the leukocyte subgroups present in Peyer's patches from the ileum and jejunum of Cryptosporidium-infected and healthy mice. After infection, ileal Peyer's patches showed a predominant CD8+ response, with abundant monocytes-macrophages (MOMA-2+) and nonlymphoid dendritic cells (NLDC-145+ cells). In contrast, jejunal Peyer's patches showed more T lymphocytes than ileal patches, with a predominance of CD4+ cells and many dendritic NLDC-145+ cells and MOMA-2+ cells. The present results showed that ileal and jejunal Peyer's patches are functionally different in response to Cryptosporidium parasites. These findings suggest a preferential involvement of jejunal Peyer's patches in T cell-dependent immunity against the parasite, whereas ileal patches may be associated with B cell expansion and maturation.




This article has been cited by other articles:


Home page
 Infect. Immun.Home page
D. Takeuchi, V. C. Jones, M. Kobayashi, and F. Suzuki
Cooperative Role of Macrophages and Neutrophils in Host Antiprotozoan Resistance in Mice Acutely Infected with Cryptosporidium parvum
Infect. Immun., August 1, 2008; 76(8): 3657 - 3663.
[Abstract] [Full Text] [PDF]

Home page
 Am J Trop Med HygHome page
C. Chansang and P. Kittayapong
Application of Mosquito Sampling Count and Geospatial Methods to Improve Dengue Vector Surveillance
Am J Trop Med Hyg, November 1, 2007; 77(5): 897 - 902.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
A. Baishanbo, G. Gargala, A. Delaunay, A. Francois, J.-J. Ballet, and L. Favennec
Infectivity of Cryptosporidium hominis and Cryptosporidium parvum Genotype 2 Isolates in Immunosuppressed Mongolian Gerbils
Infect. Immun., August 1, 2005; 73(8): 5252 - 5255.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1994 by the American Society of Tropical Medicine and Hygiene.