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Studies on Echinococcus Alveolaris (Klemm, 1883), from St. Lawrence Island, Alaska. III. The Histopathology caused by the Infection of E. Alveolaris in white Mice¹

The liver was found to be the primary site of infection for Echinococcus alveolaris; however, lung, kidney, spleen, pancreas and alimentary canal were also found to be affected. The acute cellular reaction caused by the infection and the pathological changes produced in the different organs are also described in detail. Perivascular infiltration with mononuclear cells was found to be characteristic of this infection and was observed in liver, lung and kidney. The chief characteristic of the larval stage of E. alveolaris is the type of lesion, which behaves very much like an infiltrating neoplasm.

¹ Portion of a thesis submitted as partial fulfillment of the requirements for the degree of Doctor of Philosophy, University of Illinois. This work was done under the direction of Dr. Lyell J. Thomas, whose advice and assistance are gratefully acknowledged by the author.