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Am. J. Trop. Med. Hyg., 5(5), 1956, pp. 863-868
Copyright © 1956 by The American Society of Tropical Medicine and Hygiene

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Thrombocytopenic Purpura due to Fuadin (Stibophen)

Julio V. Rivera, Hector F. Rodriguez AND E. Pérez-Santiago
The San Patricio Veterans Administration Hospital, San Juan and Bayamón District Hospital, and the School of Medicine, University of Puerto Rico

A case of immune thrombocytopenic purpura due to Fuadin has been reported. The reaction occurred on 2 occasions when the drug was given. Administration of plasma from this patient to a recipient who also received Fuadin produced thrombocytopenia without purpura. It is postulated that thrombocytopenic purpura in this patient was due to the occurrence of a drug-antibody complex capable of destroying or agglutinating platelets and depressing megakaryocyte activity.







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Copyright © 1956 by the American Society of Tropical Medicine and Hygiene.