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Effects of Tetrachlorethylene without a Purge, Followed by Ferrous Sulfate in Ancylostomiasis

Carr et al. (1954), working in the Dominican Republic, showed that, in the treatment of ancylostomiasis, tetrachlorethylene is more effective in removing worms and provokes less complaint on the part of the patients when it is not followed by a saline purgative. Because of the practical importance of such a finding, we were interested in discovering whether the same therapeutic procedure would be equally effective on the African continent. At the same time, we took occasion to observe the effect of ferrous sulfate treatment on hemoglobin regeneration.

Materials and Methods. For these purposes, 165 patients with hemoglobin values ranging from 25 to 85 per cent (Sahli) were treated as follows.

1) Tetrachlorethylene, in a dosage of 0.12 ml./kg. (maximum dose, 5 ml.) was administered every 4 days until all worms were removed. On the evening before the treatment, patients had a light dinner without fats, and the drug was given next morning on an empty stomach.

¹ Address: Missão do Sono, Bissau, Portuguese Guinea, West Africa