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Am. J. Trop. Med. Hyg., 5(4), 1956, pp. 690-695
Copyright © 1956 by The American Society of Tropical Medicine and Hygiene

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An Epidemic of Histoplasmosis in Venezuela

Humberto Campins, Carlos Zubillaga Z., Luis Gomez Lopez AND Manuel Dorante
Servicio de Laboratorio, Hospital Central and Sanatorio Antituberculoso, Barquisimeto, Venezuela

The serious illness, due to a pulmonary mycosis, of two members of a group which had been exploring a cave in the State of Lara, Venezuela, led to an examination of 10 other members of the group, all of whom gave positive reactions to histoplasmin, with confirmatory chest x-rays in 5 cases, and positive complement fixation tests in 7. Soil samples were taken from various parts of the cave, from 5 of which 4 cultures of Histoplasma capsulatum were obtained. In a second group of 5 visitors to the cave, one new case developed in the only member negative to histoplasmin prior to the visit, in spite of a respirator mask which he wore. The clinical and x-ray pictures, the appearance of complement-fixation antibodies, and the conversion of a negative to a positive histoplasmin reaction proved this to be a case of primary pulmonary histoplasmosis.




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C. C. Campbell, G. B. Hill, and B. T. Falgout
Histoplasma capsulatum Isolated from Feather Pillow Associated with Histoplasmosis in an Infant
Science, June 22, 1962; 136(3521): 1050 - 1051.
[Abstract] [PDF]




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Copyright © 1956 by the American Society of Tropical Medicine and Hygiene.