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Am. J. Trop. Med. Hyg., 5(4), 1956, pp. 681-685
Copyright © 1956 by The American Society of Tropical Medicine and Hygiene

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Hydroxychloroquine in the Treatment of Malaria

Miguel Nieto-Caicedo
Division of Malariology, Department of Public Health and Social Welfare, Venezuela

Hydroxychloroquine was given orally to 50 patients with P. vivax infections, either in a single dose or in a one-day treatment of several doses. Both parasitemia and temperature were controlled on the average in less than 2 days, with no unfavorable effects noted. This study in Venezuela confirms observations by others that hydroxychloroquine exhibits antimalarial activity against P. vivax comparable to that of other 4-aminoquinolines but appears to be better tolerated.






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Copyright © 1956 by the American Society of Tropical Medicine and Hygiene.