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Chemotherapy of Malaria

by G. COVELL, G. R. COATNEY, J. W. FIELD AND J. SINGH. 121 pp., (French edition in preparation). Geneva, World Health Organization: Monograph Series, No. 27. 1955. $3.25 (cloth) 17/6, Sw. fr. 10.-

Until the end of World War I, quinine and other cinchona alkaloids were the only specific drugs available for the treatment of malaria, but in recent years the development of synthetic antimalarials has proceeded so rapidly and successfully that "there are few infections more responsive to well-directed therapy than human malaria, and fewer in which therapy can be applied with results so satisfying." The authors, appointed to the task by the World Health Organization, present an authoritative assessment of the properties and potentialities of the newer drugs which will be particularly useful to the medical profession. This small book is very comprehensive, giving within the compass of about 100 pages a historical review, definitions of terms, a practical description of the compounds in common use, a discussion of drug resistance and a guide to the clinical use of antimalarial drugs. The book contains a selected bibliography of about 200 titles, and a good index.