AJTMH ASTMH MEMBERSHIP INFORMATION: astmh@astmh.org
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 5(3), 1956, pp. 501-503
Copyright © 1956 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by van Assendelft, F.
Right arrow Articles by Most, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by van Assendelft, F.
Right arrow Articles by Most, H.

The Use of Glaucarubin (a Crystalline Glycoside Isolated from Simarouba Glauca) in the Treatment of Human Colonic Amebiasis

F. van Assendelft, J. W. Miller, D. T. Mintz, J. A. Schack, P. Ottolenghi AND H. Most
Department of Preventive Medicine, New York University-Bellevue Medical Center, New York City and the Tropical Disease Diagnostic Clinic, Lower East Side Health Center, New York City Health Department, New York City

Glaucarubin, a crystalline glycoside isolated from Simarouba glauca and found to have amebicidal properties in vitro and in experimental animal amebiasis, was evaluated in the treatment of the human infection. Cure rates in the order of 70 per cent were observed following treatment by mouth for 10 days with daily doses of 5 mg./kg. (maximum daily dose 300 mg.). With the exception of vomiting in 2 patients and a transitory decrease in leucocyte count in another, the drug was well tolerated in 113 patients.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1956 by the American Society of Tropical Medicine and Hygiene.